Gout and its comorbidities: implications for therapy
نویسندگان
چکیده
منابع مشابه
Gout and its comorbidities.
Gout is a chronic disease in which excessively high levels of serum urate (hyperuricemia) result in tissue depositions of sodium urate crystals and intermittent inflammatory attacks. Patients who have gout frequently experience a range of comorbidities, which complicates management and affects long-term prognosis. We review some of the more important of these comorbidities and consider the exte...
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An association of gout with hypertension, dia‐ betes, kidney disease and cardiovascular disease has been observed since the late 19th century. This association is not only observed with frank hyperuricemia defined as more than 6 mg/dl (360 μm/l) in women and more than 6.5–7 mg/dl (420 μm/l) in men but also with uric acid levels considered to be in the normal to high range of >5.2–5.5 mg/dl (310...
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Gout is an acquired autoinflammatory disorder characterized by severe joint inflammation and deposition of monosodium urate crystals in the joints. Hypertension (HTN), diabetes, chronic renal failure, obesity, insulin resistance, hypercholesterolemia, metabolic syndrome and cardiovascular disease are common comorbidassociated conditions [1–5]. Normotensive individuals with baseline hyperuricemi...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2012
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kes211